Keto Buffalo Chicken Enchiladas

Annie Lampella @ Ketofocus

By Annie Lampella, Pharm.D.

Published September 27, 2020 • Updated February 1, 2026

Reader Rating
4.8 Stars (6 Reviews)

This post may contain affiliate links. See my disclosure policy.

These buffalo chicken enchiladas are a finger-licking twist on the spicy Mexican casserole. This 30 minute meal combines chicken, creamy buffalo sauce and blue cheese to create an easy low-carb dinner the whole family will love.

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Keto Buffalo Chicken Enchiladas

4.8 (6) Prep 10m Cook 12m Total 22m 4 servings

Ingredients

  • 3 tablespoon butter, divided
  • 2 cups cooked shredded chicken
  • 1 cup buffalo sauce, divided
  • 1/2 teaspoon lemon juice
  • 1/4 cup sour cream
  • 4 ounces cream cheese, softened
  • 8 slices deli chicken meat
  • 3 tablespoons water
  • 1 cup shredded Mexican blend cheese
  • 1/4 cup crumbled blue cheese
  • 2 green onions, sliced

Step by Step Instructions

Step by Step Instructions

1
Preheat oven

Preheat oven to 400 degrees.

oven set at 400 degrees
2
Sauce the chicken

In a large skillet, add 1 tablespoon of butter and melt over medium high heat. Add chicken and 1/2 cup buffalo sauce. Simmer until sauce has thickened.

red led light with 400 on it
3
Make it creamy

Remove skillet from heat, stir in lemon juice, sour cream and cream cheese. Combine until smooth.

buffalo chicken simmering in a skillet
4
Make buffalo enchilada sauce

In a separate bowl, melt remaining 2 tablespoons of butter using a microwave or a small saucepan. Add remaining buffalo sauce and water. Stir to combine.

creamy buffalo chicken mixture in a skillet
5
Pour sauce on the bottom

Pour 1/3 of buffalo sauce mixture to the bottom of a 3-quart casserole dish.

Buffalo sauce on bottom of baking dish
6
Assemble enchiladas

Take one slice of chicken and scoop a large spoonful of buffalo chicken mixture to the center of the chicken slice. Roll and place seam side down along the edge of the casserole dish. Continue with remaining chicken slices.

red sauce on the bottom of a baking dish
7
Final sauce pour

Pour remaining buffalo sauce mixture on top of enchiladas.

scooping buffalo chicken mixture onto a slice of deli meat.
8
Cheese on top

Top with shredded cheese and blue cheese.

buffalo wing red sauce on top of keto enchiladas
9
Bake

Bake at 400 degrees for 12 minutes. Top with sliced green onions.

cheese and blue cheese sprinkled on enchiladas with ingredients nearby
Nutrition Per Serving
495 Calories
31.8g Fat
48.3g Protein
2.3g Net Carbs
2.5g Total Carbs
4 Servings
Nutrition disclaimer

The nutrition information provided is an estimate and is for informational purposes only. I am a Doctor of Pharmacy (Pharm.D.); however, this content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or other qualified health provider before making any lifestyle changes or beginning a new nutrition program.

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Low Carb Buffalo Chicken Enchiladas Recipe

two cheese covered enchiladas on a plate with a side of salad If you look at my recipes, it’s obvious we love making enchiladas. They are easy to make, the whole family loves them, and they are something I can prep up ahead of time and freeze. These buffalo chicken enchiladas are a fun take on the classic Mexican casserole. Creamy buffalo sauce is smothered over pre-cooked chicken and rolled in a protein tortilla, aka sliced deli chicken, topped with a buttery buffalo wing sauce and coated with two types of cheese – Mexican blend and blue cheese. This entire meal can come together in less than 30 minutes. It’s the ideal dinner for busy nights! chicken enchiladas in a casserole dish with two missing

Is Buffalo Sauce Keto?

Yes, buffalo sauce is keto friendly. If you look at the nutrition label, most of them contain zero carbs. I use this buffalo sauce by Noble Made, but you can find Frank’s Buffalo Sauce in pretty much all grocery stores. The main takeaway is to look for a buffalo sauce that doesn’t contain any added sugars or carbs. To make the buffalo sauce even better, we add a couple tablespoons of butter to the sauce. This punches up the flavor and adds some extra fat to help keep us full! stirring buffalo sauce into a skillet of shredded chicken

Chicken Slices as Protein Tortillas

One of the easiest and most accessible options for a tortilla is to use deli chicken slices. I usually have sliced chicken on hand for my kids. I’m always making some sort of low carb lasagna or casserole so I try to keep at least a half a pound of sliced chicken on hand. If you don’t have chicken, turkey or ham works too! Another good reason to use sliced chicken as your tortillas when making buffalo chicken enchiladas is that it provides a little extra protein to the dish without adding extra carbs. a couple rows of enchiladas in a casserole dish while grabbing sliced deli meat

Other Tortilla Substitutions

If you didn’t want to use deli chicken slices to make your buffalo chicken enchiladas, I have some other keto-friendly options for you.
  • Low Carb Tortillas – There are some brands that are making low carb tortillas. Mission is a common brand that you can find at the grocery store. There are around 6 grams net carbs per tortilla; however, they are made from wheat protein and are not gluten free. If you are avoiding gluten, it’s best to avoid this option. Instead, I make my own using my homemade tortilla recipe.
  • Cabbage – I don’t really care for this option but many people do like the flavor the cabbage leaves provide.
a bowl of shredded chicken

30 Minute Weeknight Dinner

I love making easy dinners for busy families. Since our family is always on the go, I rely on simple dinners that can either be prepped ahead of time or made quickly when I get home from work. This buffalo enchilada recipe does just that. Plus, it uses pre-cooked chicken. If I have some shredded chicken leftover that I made in the instant pot or swing by the grocery store and pick up a rotisserie chicken, I can make this dinner in minutes without adding on additional time to cook the chicken. If you only have raw chicken, you can still make this recipe. Just cook the chicken in the butter until cooked through. This adds an additional 8-10 minutes to your cook time.

Freezer Safe & Storage Info

Even better than being easy to prepare, this dinner is also freezer safe! You can assemble the entire enchilada casserole and before baking, just cover and freeze for up to a month. To cook from frozen bake at 400 degrees for 45 – 60 minutes.
Keto Buffalo Chicken Enchiladas

Frequently Asked Questions

Can I use rotisserie chicken instead of cooked shredded chicken?

Yes! Rotisserie chicken works great here and adds extra flavor to your enchiladas.

What if I don't have buffalo sauce? Can I substitute it?

Yes! Mix hot sauce with some melted butter for a similar taste, or try a spicy barbecue sauce for a different twist.

How can I make this recipe dairy-free?

Swap the cream cheese and sour cream for dairy-free alternatives like cashew cream or coconut cream.

How should I store leftovers?

Store leftovers in an airtight container in the fridge for up to 3 days. Reheat in the microwave or oven before serving.

Is this recipe suitable for meal prep?

Yes! These enchiladas are perfect for meal prep. Assemble them ahead of time and store in the fridge or freeze for later.

About the Author
Annie Lampella, Pharm.D.

Annie Lampella, Pharm.D.

Annie is a Doctor of Pharmacy, mom, and the recipe creator behind KetoFocus. With a B.S. in Genetics from UC Davis, she has over 14 years of experience developing family-friendly keto recipes based on the science of human metabolism.

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  1. T
    Travis R. Apr 14, 2025

    Can I use rotisserie chicken instead of cooking and shredding my own?

    1. Annie Lampella
      Annie May 30, 2025

      Yes, absolutely! I use a rotisserie chicken often as a shortcut.

  2. J
    Julai Feb 16, 2023

    Hi Annie,
    I soo love your site and happy to have stumbled into it. I am trying to transition my family into eating low-carb and looking for recipes that are delicious. Most of the recipes I tried before didn't pass the taste test for my picky husband and 2 toddler boys. The recipes I tried in your site passed the test and husband didn't think they were low carb. Is there a homemade substitute for Buffalo sauce? We live in Spain and I don't think we have this sauce here.

    1. Annie Lampella
      Annie Feb 19, 2023

      I'm so glad you are enjoying the recipe. Do you have Frank's red hot sauce? There are lots of recipes on the internet for homemade buffalo sauce using Frank's Red Hot Sauce as a base. Maybe that will work.

  3. T
    Taphandle1 Nov 2, 2022

    My son can not believe it was all Keto!

  4. G
    girl1dir Jun 30, 2021

    Must say, I was a little cautious of this being good. I was wrong, it was GREAT last night! I even said, "I think I like this better than any enchiladas I have had at a restaurant." Thank you for this recipe!

  5. S
    Susan Fox Mar 28, 2021

    Made this last night. I loved the flavors snd the chicken was so moist snd tender. I doubled the recipe and used half Frank’s Hot Buffalo Sauce and have his regular Buffalo sauce. I thought the heat was just right, but my husband said it was burning his mouth. Next time I’ll use less of hot sauce for him. Great recipe!!

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