Low Carb Keto Lasagna

Annie Lampella @ Ketofocus

By Annie Lampella, Pharm.D.

Published July 20, 2019 • Updated March 6, 2026

This post may contain affiliate links. See my disclosure policy.

I use deli chicken instead of noodles in this keto lasagna. No watery layers, zero prep, 30 minutes to the oven. 34g protein, 4g net carbs. Day 2 tastes better than Day 1.

I made watery lasagna for three years before I admitted the problem. Zucchini slices leak liquid no matter how long you salt them. The whole dish turns into soup by day two, and you spend 30 minutes prepping vegetable ‘noodles’ before you can even start layering.

When I first heard about using deli chicken as the noodle replacement, I thought it sounded desperate. But I was tired of draining pools of liquid, so I tested it. The chicken holds its structure without releasing water. Vegetables are 90% water. When you bake them, that moisture goes somewhere (usually into your ricotta layer). Protein doesn’t do that. Thinly sliced deli chicken acts like a structural layer that soaks up sauce instead of releasing it. If you’ve tried my baked ziti or skillet lasagna, you know I love a good Italian casserole. This one is the easiest.

This keto lasagna takes 30 minutes from start to oven. No salting zucchini. No making fathead dough. No pre-cooking anything. You open packages, layer, bake. I’ve tested this against every other low carb noodle method (zucchini, eggplant, cabbage, fathead, shirataki) and nothing else comes close.

It took me four test batches to get the layering right. My first attempt had dry edges where the chicken wasn’t fully covered. The second was too saucy and took 8 extra minutes to set. By round three, I figured out you need to overlap the chicken slices slightly and add extra sauce at the corners. My fourth batch came out perfect at exactly 20 minutes. The cheese was bubbly and starting to brown, but the chicken stayed tender.

The protein surprised me. One serving has 34g protein, more than five eggs. That’s triple what you get from a zucchini version. My oldest son asked why I stopped doing keto when he saw me serve this. He couldn’t tell it wasn’t regular lasagna. My husband requested it twice in the same week, which has never happened with any other version. I pair this with a side salad or my spaghetti for a full Italian night.

Day two tastes better than day one. The chicken soaks up more sauce overnight. Most noodle-sub versions get worse in the fridge. This one improves. I’ve reheated portions five days later and they still held together.

What I’ve learned after 100+ batches

The ricotta trick: Commenter Joann suggested mixing an egg and parmesan into the ricotta. I tried it, and now I won’t make it any other way. The ricotta spreads evenly and sets into a creamier layer.

Simmer your meat sauce at least 5 minutes after adding marinara. Skipping this is the second biggest cause of a watery result.

Check the label on your deli meat. I used honey-glazed chicken once and the caramelized sugar made everything weirdly sweet.

Use a deep dish, not a 9×13. Readers Cathy and Abby both found that a wide, shallow dish spreads the layers too thin. I use an 8×8. If you want a 9×13, double the recipe for 3 proper layers.

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Low Carb Keto Lasagna

4.8 (73) Prep 10m Cook 20m Total 30m 8 servings

Ingredients

  • 1 lb ground beef or Italian sausage
  • 12 oz of low-carb marinara sauce or low sugar tomato sauce
  • ¾ lb sliced chicken or turkey (from the deli counter)
  • 10 tablespoons whole milk ricotta cheese
  • 3 cups shredded mozzarella cheese

Step by Step Instructions

Step by Step Instructions

1
Brown the beef

Brown the ground beef in a skillet over medium-high heat. Season with salt & pepper. Add additional seasoning like basil, Italian seasoning, garlic powder, anise, or oregano if desired.

ground beef in a skillet cooking
Tip For even more flavor, add diced onions, mushroom, bell peppers if desired.
Ingredients for this step
  • 1 lb ground beef
  • salt
  • pepper
2
Meat sauce

Once the meat is cooked until no longer pink, add in the marinara sauce. Stir to combine and let simmer on low for 5 minutes. Remove from heat.

marinara sauce mixed in with ground beef
Tip Sometimes, I'll add a splash of heavy cream and a sprinkle of parmesan cheese to add flavor and balance.
Ingredients for this step
  • 12 oz marinara sauce
3
Layer the ingredients

In a casserole dish, spread a small amount of ground beef mixture on the bottom. Add a layer of chicken slices. Followed by another layer of ground beef. Top with 5 dollops of ricotta cheese and ¼ of the mozzarella cheese. Repeat the layers 2-3 times. End the layers with ground beef mixture and then remaining mozzarella cheese.

layering lasagna in a casserole dish
Tip YouTube subscriber Joann suggests to mix an egg and some parmesan cheese into the ricotta. It's tastier and helps the ricotta spread evenly.
Ingredients for this step
  • 3/4 lb sliced chicken or turkey
  • 10 oz ricotta cheese
  • 3 cups shredded mozzarella cheese
4
Bake your lasagna

Bake in the oven at 400F for 15 minutes or until cheese is bubbly on top.

baked low-carb lasagna in a dish
Nutrition Per Serving
389 Calories
26g Fat
34g Protein
4g Net Carbs
4.7g Total Carbs
8 Servings
Nutrition disclaimer

The nutrition information provided is an estimate and is for informational purposes only. I am a Doctor of Pharmacy (Pharm.D.); however, this content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or other qualified health provider before making any lifestyle changes or beginning a new nutrition program.

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Low Carb Keto Lasagna

Frequently Asked Questions

Why does my lasagna turn out watery?

Nine times out of ten, it's the noodle substitute. I dealt with this for years using zucchini. Vegetables release moisture during baking and turn everything into soup. That's why I switched to deli chicken. If you're already using chicken and still getting liquid, your meat sauce is probably too thin. I simmer mine at least 5 minutes before layering. Don't add extra sauce beyond what the recipe calls for, and let it rest 10 minutes before cutting so the layers set.

What size baking dish should I use?

I use an 8x8 or similar deep dish. Readers Cathy and Abby both found that a 9x13 spreads the layers too thin and you end up with a flimsy result. If you want to use a 9x13, double the recipe so you get 3 full layers. The deeper dish gives you that thick, stacked bite where every forkful has sauce, cheese, and chicken.

Can I use turkey, ham, or other deli meats?

I've made this with all three. Turkey works fine but tends to be slightly drier. Chicken has a more neutral flavor that disappears into the dish, which is why I reach for it 9 out of 10 times. A reader named Bill tried ham and loved it, and I've done that too when I ran out of chicken. Either way, get it sliced thin at the deli counter (about 1/16 inch). Pre-packaged slices are usually too thick.

What can I substitute for ricotta cheese?

I've tested three alternatives. Cream cheese makes the layers richer and creamier (my go-to swap). Cottage cheese blended smooth with an egg is lighter and easier to spread. My husband actually preferred the cottage cheese version. Mascarpone works if you want something more indulgent. Use full-fat for all three. The low-fat versions get grainy when baked. For dairy-free, I haven't found a substitute that holds up in the oven. The cheese layers are structural in this dish.

Should I use Italian sausage or ground beef?

I've used both dozens of times. Ground beef gives you a cleaner, more traditional flavor that lets the sauce and cheese stand out. Italian sausage adds fennel and heat that makes the whole dish taste more complex. My favorite move is a 50/50 mix when I want depth without it tasting like a sausage casserole. Reader TT used spicy sausage with Rao's arrabbiata and said it was incredible.

Can I use EggLife wraps instead of deli chicken?

A reader named Suzi tested this and said it worked great. I tried it after her comment and she's right. EggLife wraps give you a thinner, more noodle-like layer. The trade-off is less protein per serving. For a fully meatless low carb version, EggLife wraps with the ricotta and marinara layers hold together well, but I'd add a protein source somewhere else in the meal.

How do I freeze and reheat this?

I freeze mine for up to 3 months regularly. My method: assemble completely, wrap tightly in plastic wrap, then foil. I label it with the date because I always think I'll remember and I never do. Bake from frozen at 375F for 45-50 minutes covered, then 15 minutes uncovered. I've tested both thawing overnight and baking from frozen. The from-frozen method gives me more consistent layers because nothing shifts during thawing.

Will my non-keto family notice the difference?

This is the question I get most often. My oldest son asked why I stopped eating keto when he saw me serve this. He thought it was regular lasagna. The texture difference from real pasta is minimal because the noodles aren't the star anyway. The sauce and cheese are. I've served this to guests without mentioning the swap, and no one has ever asked.

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Every noodle substitute I've tested (ranked)

I’ve tested every low carb noodle option I could find, and I keep coming back to thinly sliced deli chicken. But here are the alternatives so you can decide what works for your kitchen.

Newer to the market are Palmini Lasagna Noodles. These are made from hearts of palm. I’ve used them a few times. They work, but the texture is softer than I prefer and they add 6 grams of net carbs per can.

For a zero carb option on keto, I recommend EggLife Wraps or homemade egg wraps. Once baked, they have the texture of a noodle and don’t taste eggy. Reader Suzi confirmed this works well. I’ve also tested sliced zucchini (my full take is in the zucchini lasagna recipe), but the water release was always a dealbreaker for me in this dish.

How I store and freeze this for meal prep

Make ahead instructions

I meal prep this almost every other week. Brown the ground beef, then layer the sauce, deli chicken, beef mixture, and cheese in your baking dish. Wrap with plastic wrap and foil. I store mine in the freezer for up to 3 months. I’ve pushed it to 6 months and it was still fine, but the flavor fades after month three.

Should you freeze before or after baking?

I’ve done it both ways. Freezing before baking gives me better results. The layers hold their shape and the cheese melts fresh. If you freeze after baking, let it cool completely first, then wrap tightly. To bake from frozen, go 375F for 45-50 minutes covered, then 15 uncovered. If you thaw overnight in the fridge first, bake at 400F for 20-25 minutes. I prefer the from-frozen method because I never remember to move it the night before.

The marinara sauce that makes or breaks this dish

I’ve tested a lot of store-bought marinara sauces over the years. For this recipe, I keep coming back to Rao’s Marinara Sauce. It has 3g net carbs per half cup, no added sugar, and the flavor is close to homemade. It’s more expensive than most jarred sauces, but the quality difference is noticeable when the sauce is front and center.

If you’re on a budget, a homemade marinara works great here too. I make a batch on meal prep day and freeze portions in mason jars (leave headroom for expansion). I use the same thick sauce approach for my chicken parmesan. A thick sauce is critical because a thin, watery marinara will make your lasagna soupy no matter what noodle substitute you use.

jar of raos marinara sauce

Variations I've actually tested in my kitchen

Cream Cheese

For a creamier version, I replace the ricotta with cream cheese. It melts into the layers and makes everything richer and smoother, especially after reheating the next day. Cream cheese is my favorite ricotta alternative if you’re not a fan (and based on the comments, plenty of you aren’t).

Cottage Cheese

I blend cottage cheese in a food processor for about 30 seconds, then mix in an egg and parmesan the same way I do with ricotta. The texture is lighter and it spreads more easily. My husband actually preferred this version. Use full-fat. The low-fat stuff gets grainy when baked.

Italian Sausage vs Ground Beef

Ground beef gives you a cleaner, more traditional flavor. Italian sausage adds fennel and heat that makes the sauce taste more complex without extra seasoning. I usually go 50/50 when I want depth without overwhelming the cheese. If you like sausage, try my stuffed Italian sausage recipe for browning technique.

Add a Spinach Layer

Reader Mark added spinach to each layer and it worked. The spinach won’t water down the dish because the chicken layer keeps everything stable (zucchini would’ve been a disaster with the extra moisture). I’ve done this with both fresh and frozen spinach. If frozen, squeeze out every drop of water first.

Puree Mushrooms and Bell Pepper

If you’ve got picky eaters or kids who suddenly ‘don’t like vegetables anymore,’ this is one of my favorite tricks. I saute mushrooms and bell pepper, toss them in the blender, and stir that into the sauce. Nobody notices and the sauce tastes better.

Add More Spices

This is where you make it yours. I almost always add extra basil, oregano, and garlic powder because I like my red sauce bold. A pinch of red pepper flakes adds heat. And anchovy paste sounds weird, but it melts into the sauce and makes everything taste deeper and more savory. This same approach works in my enchilada lasagna too.

About the Author
Annie Lampella, Pharm.D.

Annie Lampella, Pharm.D.

Annie is a Doctor of Pharmacy, mom, and the recipe creator behind KetoFocus. With a B.S. in Genetics from UC Davis, she has over 14 years of experience developing family-friendly keto recipes based on the science of human metabolism.

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4.8 Stars (73 Reviews)
  1. A
    Ashley Apr 22, 2026

    Used Italian sausage since it's what I had. Sauce turned out way richer than expected for a first try. Leftovers were even better the next day, didn't see that coming.

  2. C
    Crystal Apr 21, 2026

    First keto attempt and I was skeptical about deli chicken for noodles, but the layers held. Turned out better than I expected. Is the day 2 thing real, or is that just me looking for an excuse?

  3. K
    Keisha Apr 20, 2026

    Made a double batch on Sunday and the day 2 thing is SO real (I actually hid a container in the back of the fridge so nobody would touch it). The deli chicken trick means no soggy layers even after reheating, which is the thing that always kills casseroles for me.

  4. R
    Rita Anderson Apr 18, 2026

    Six batches in and I still look forward to day-two leftovers more than the fresh pan. Ricotta and marinara soaking overnight somehow makes it taste like way more effort than it is. Deli chicken finally got me off zucchini noodles for good.

    1. Annie Lampella
      Annie Lampella Apr 20, 2026

      Zucchini pulls moisture out, chicken pulls it in. Completely different result by day two.

  5. S
    Sarah Apr 7, 2026

    Portioned this into containers Sunday, ate the last one Wednesday, and the deli chicken layers on day four had soaked up the sauce like it'd been braising all afternoon.

    1. Annie Lampella
      Annie Lampella Apr 12, 2026

      Day four is the peak and I've been saying this for years. The chicken just keeps pulling in the sauce in a way pasta actually can't. Zucchini would've been soup by Wednesday.

  6. M
    Maria Apr 1, 2026

    The flavor was there, and chicken holds up way better than zucchini ever does for me. Ricotta in the middle was a little bland, though the rest of the dish made up for it. Next time I'd mix Italian seasoning into the ricotta before layering. Day 2 was noticeably better, and that part the recipe nailed.

    1. Annie Lampella
      Annie Lampella Apr 5, 2026

      Italian seasoning in the ricotta, yes. I mix in garlic powder too. Plain ricotta just gets lost between those layers.

  7. M
    Mike Mar 23, 2026

    Just grabbed everything for this and realized I don't actually own a casserole dish (just moved and my kitchen stuff is still kind of scattered). Would a 10-inch cast iron skillet work? I'm a little nervous the layers won't sit right with the deli chicken slices if the shape is off.

    1. Annie Lampella
      Annie Lampella Mar 24, 2026

      Cast iron works. 10-inch is close to an 8x8 so the layers won't go too thin. The chicken slices just overlap to fill the round shape, nothing to worry about there. Cast iron runs hot though, so check it 3-4 minutes early.

  8. M
    Megan Mar 22, 2026

    My son has been skeptical of every keto swap I've tried, so I didn't mention the deli chicken standing in for noodles. He finished his bowl, then asked what was different because 'the layers looked weird.' He meant it as a question, but I took it as a win.

    1. Annie Lampella
      Annie Lampella Mar 23, 2026

      'The layers looked weird' is basically a 5-star review from a skeptical kid. My oldest said the same thing the first time and then had seconds.

  9. G
    Gina Mar 10, 2026

    Used spicy Italian sausage instead of ground beef and the heat works through each layer in a way the plain beef version doesn't. Only thing I'd change is adding another layer, the recipe as written comes out a little thin for my casserole dish. Still making it again.

    1. Annie Lampella
      Annie Lampella Mar 10, 2026

      The sausage version might be better than my original. That heat carries through every layer in a way beef just doesn't. On the thin layers - what size dish are you using? 9x13 is the culprit. Either go 8x8 or double the recipe if you want the height.

  10. M
    Marcus N. Mar 3, 2026

    Deli chicken idea = genius, and yes the watery layers are a real problem with every keto lasagna I've made. Only thing: broil the top 2 minutes at the end, mine came out pretty pale. Round two Sunday.

    1. Annie Lampella
      Annie Lampella Mar 4, 2026

      Good catch on the broil. Two minutes right at the end makes such a difference on the color. Mine can look pale straight out of the oven too, so I kick the broiler on for a couple minutes. Report back Sunday.

  11. J
    Jordan Feb 25, 2026

    My mom made lasagna every Sunday when I was growing up and when I went keto I figured that was just gone. First bite of this brought me back so hard I actually called her to read the recipe out loud over the phone. The ricotta and mozzarella layers together, that's the thing that got me. Four stars because I burned the edges on mine, but I'm going back in this weekend with a closer eye on it.

    1. Annie Lampella
      Annie Lampella Feb 26, 2026

      That story about calling your mom - that's the whole point. For the burned edges, tent foil over it for the first 20 minutes and pull it the last 10. Mine used to run dark too before I figured that out.

  12. J
    Jo Aug 14, 2024

    Do you use bagged shredded mozzarella or grate from fresh? thank you

    1. Annie Lampella
      Annie Lampella Aug 14, 2024

      I just use the bagged shredded cheese in this lasagna recipe.

  13. C
    Cathy Bumgardner Jan 27, 2024

    This recipe is delicious! If you want to use an 8x10 dish or a 9x12 dish, double the recipe to layer the steps 3 times as stated in the recipe. Or you’ll only have enough product for about 1.5 layers. And add a lot of onions, green peppers, and mushrooms. Plus other veggies!

    The chicken in place of noodles is brilliant and delicious! Just make sure you have enough to feed everyone this delicious main course.

    1. Annie Lampella
      Annie Lampella Jan 28, 2024

      Yes on the larger dish! I should put that in the recipe notes. And the veggie adds work really well here since the chicken layer keeps everything from getting watery (zucchini would've been a disaster).

  14. C
    Carolyn WOOD Jan 16, 2024

    Amazing!!!
    I made it in a small cheesecake tin.
    Omg will be making this again .
    Thankyou Annie

    1. Annie Lampella
      Annie Lampella Jan 18, 2024

      Cheesecake tin is clever, the layers stay so clean when you unmold it.

  15. B
    Bill Mullican Oct 6, 2023

    I tried this recipe, instead of turkey or chicken, I used Ham, it came out absolutely amazing.
    Lasagna is my favorite. I so happy I found this recipe...

    1. Annie Lampella
      Annie Lampella Oct 8, 2023

      Ham works surprisingly well in this. Already added it to my FAQ, mentioned you by name.

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